3VRB

Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil and substrate fumarate

Summary for 3VRB

• Entry DOI: 10.2210/pdb3vrb/pdb
• Related: 3VR8
• Descriptor: Flavoprotein subunit of complex II, PROTOPORPHYRIN IX CONTAINING FE, N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl)benzamide, ... (12 entities in total)
• Functional Keywords: ascaris suum, membrane protein, reductase, mitochondrial membrane, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Ascaris suum (Pig roundworm); More
• Cellular location: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side : Q33862 O44074; Mitochondrion inner membrane ; Multi-pass membrane protein : P92507
• Total number of polymer chains: 8
• Total formula weight: 289071.41

Authors

Shimizu, H.,Shiba, T.,Inaoka, D.K.,Osanai, A.,Kita, K.,Sakamoto, K.,Harada, S. (deposition date: 2012-04-07, release date: 2012-07-11, Last modification date: 2023-11-15)

• Primary citation: Shimizu, H.,Osanai, A.,Sakamoto, K.,Inaoka, D.K.,Shiba, T.,Harada, S.,Kita, K.; Crystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suum; J.Biochem., 151:589-592, 2012; PubMed: 22577165; DOI: 10.1093/jb/mvs051

Experimental method

X-RAY DIFFRACTION (2.91 Å)