3VLG

Crystal structure of the W150A mutant LOX-1 CTLD showing impaired OxLDL binding

Summary for 3VLG

Entry DOI	10.2210/pdb3vlg/pdb
Related	1YXJ 1YXK
Descriptor	Oxidized low-density lipoprotein receptor 1 (2 entities in total)
Functional Keywords	c-type lectin-like domain, oxidized ldl receptor, membrane protein, lipid binding protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type II membrane protein: P78380
Total number of polymer chains	1
Total formula weight	16320.61
Authors	Nakano, S.,Sugihara, M.,Yamada, R.,Katayanagi, K.,Tate, S. (deposition date: 2011-12-01, release date: 2012-04-18, Last modification date: 2023-11-08)
Primary citation	Nakano, S.,Sugihara, M.,Yamada, R.,Katayanagi, K.,Tate, S. Structural implication for the impaired binding of W150A mutant LOX-1 to oxidized low density lipoprotein, OxLDL Biochim.Biophys.Acta, 1824:739-749, 2012 Cited by PubMed: 22369967 DOI: 10.1016/j.bbapap.2012.02.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation