3VI2
Crystal Structure Analysis of Plasmodium falciparum OMP Decarboxylase in complex with inhibitor HMOA
Summary for 3VI2
| Entry DOI | 10.2210/pdb3vi2/pdb |
| Descriptor | Orotidine 5'-phosphate decarboxylase, 4-(2-hydroxy-4-methoxyphenyl)-4-oxobutanoic acid, SODIUM ION, ... (4 entities in total) |
| Functional Keywords | orotidine 5 f-monophosphate decarboxylase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Plasmodium falciparum |
| Total number of polymer chains | 2 |
| Total formula weight | 76249.88 |
| Authors | Takashima, Y.,Mizohata, E.,Krungkrai, S.R.,Matsumura, H.,Krungkrai, J.,Horii, T.,Inoue, T. (deposition date: 2011-09-16, release date: 2012-08-01, Last modification date: 2024-03-20) |
| Primary citation | Takashima, Y.,Mizohata, E.,Krungkrai, S.R.,Fukunishi, Y.,Kinoshita, T.,Sakata, T.,Matsumura, H.,Krungkrai, J.,Horii, T.,Inoue, T. The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase J.Biochem., 152:133-138, 2012 Cited by PubMed: 22740703DOI: 10.1093/jb/mvs070 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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