3VH9

Crystal structure of Aeromonas proteolytica aminopeptidase complexed with 8-quinolinol

Summary for 3VH9

• Entry DOI: 10.2210/pdb3vh9/pdb
• Related: 1AMP 1CP6 1FT7 1IGB 1LOK 1RTQ 1TXR 1XRY 2ANP 2DEA 2IQ6 2NYQ 2PRQ 3B35 3B3C 3B3S 3B3T 3B3V 3B3W 3B7I 3FH4
• Descriptor: Bacterial leucyl aminopeptidase, ZINC ION, quinolin-8-ol, ... (8 entities in total)
• Functional Keywords: 8-quinolinol, dinuclear zinc hydrolases, aminopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Vibrio proteolyticus
• Cellular location: Secreted: Q01693
• Total number of polymer chains: 1
• Total formula weight: 33248.37

Authors

Saijo, S.,Hanaya, K.,Suetsugu, M.,Kobayashi, K.,Yamato, I.,Aoki, S. (deposition date: 2011-08-24, release date: 2012-05-02, Last modification date: 2023-11-08)

• Primary citation: Hanaya, K.,Suetsugu, M.,Saijo, S.,Yamato, I.,Aoki, S.; Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn(2+) fluorophores, kinetic, and X-ray crystallographic study.; J.Biol.Inorg.Chem., 17:517-529, 2012; PubMed: 22311113; DOI: 10.1007/s00775-012-0873-4

Experimental method

X-RAY DIFFRACTION (1.29 Å)