3VH7
Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21
Summary for 3VH7
Entry DOI | 10.2210/pdb3vh7/pdb |
Related | 3VGX 3VGY |
Descriptor | Envelope glycoprotein gp160, CP32M, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | 6-helix bundle, membrane fusion inhibition, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03375 |
Total number of polymer chains | 6 |
Total formula weight | 32151.55 |
Authors | Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S. (deposition date: 2011-08-23, release date: 2012-06-13, Last modification date: 2023-11-08) |
Primary citation | Yao, X.,Chong, H.,Zhang, C.,Qiu, Z.,Qin, B.,Han, R.,Waltersperger, S.,Wang, M.T.,He, Y.,Cui, S. Structural basis of potent and broad HIV-1 fusion inhibitor CP32M J.Biol.Chem., 287:26618-26629, 2012 Cited by PubMed: 22679024DOI: 10.1074/jbc.M112.381079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.019 Å) |
Structure validation
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