3VF6
Glucokinase in complex with glucose and activator
Summary for 3VF6
Entry DOI | 10.2210/pdb3vf6/pdb |
Related | 3S41 3VEV 3VF6 |
Descriptor | Glucokinase, alpha-D-glucopyranose, 6-({(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propanoyl}amino)pyridine-3-carboxylic acid, ... (5 entities in total) |
Functional Keywords | catalysis reaction, transferase, transferase-transferase activator complex, transferase/transferase activator |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 53595.70 |
Authors | |
Primary citation | Liu, S.,Ammirati, M.J.,Song, X.,Knafels, J.D.,Zhang, J.,Greasley, S.E.,Pfefferkorn, J.A.,Qiu, X. Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS. J.Biol.Chem., 287:13598-13610, 2012 Cited by PubMed: 22298776DOI: 10.1074/jbc.M111.274126 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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