3VD1
structure of p73 DNA binding domain tetramer modulates p73 transactivation
Summary for 3VD1
Entry DOI | 10.2210/pdb3vd1/pdb |
Related | 3VD0 3VD2 |
Descriptor | Tumor protein p73, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ZINC ION, ... (4 entities in total) |
Functional Keywords | protein dna complex, beta-immunoglobulin-like fold, tumour suppressor, antitumor protein-dna complex, antitumor protein/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O15350 |
Total number of polymer chains | 16 |
Total formula weight | 220045.95 |
Authors | Ethayathulla, A.S.,Tse, P.W.,Nguyen, S.,Viadiu, H. (deposition date: 2012-01-04, release date: 2012-04-18, Last modification date: 2023-09-13) |
Primary citation | Ethayathulla, A.S.,Tse, P.W.,Monti, P.,Nguyen, S.,Inga, A.,Fronza, G.,Viadiu, H. Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109:6066-6071, 2012 Cited by PubMed: 22474346DOI: 10.1073/pnas.1115463109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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