3V96

Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)

3V96 の概要

• エントリーDOI: 10.2210/pdb3v96/pdb
• 分子名称: Metalloproteinase inhibitor 1, Stromelysin-2, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: metzincin, ob-fold, metalloproteinase, protease inhibitor, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01033; Secreted, extracellular space, extracellular matrix (Probable): P09238
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39701.38

構造登録者

Batra, J.,Soares, A.S.,Radisky, E.S. (登録日: 2011-12-23, 公開日: 2012-03-28, 最終更新日: 2012-07-25)

• 主引用文献: Batra, J.,Robinson, J.,Soares, A.S.,Fields, A.P.,Radisky, D.C.,Radisky, E.S.; Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.; J.Biol.Chem., 287:15935-15946, 2012; PubMed: 22427646; DOI: 10.1074/jbc.M112.341156

実験手法

X-RAY DIFFRACTION (1.9 Å)