3V92
S663A Stable-5-LOX
Summary for 3V92
Entry DOI | 10.2210/pdb3v92/pdb |
Related | 3O8Y 3V98 3V99 |
Descriptor | Arachidonate 5-lipoxygenase, FE (II) ION (3 entities in total) |
Functional Keywords | lipoxygenase, dioxygenase, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P09917 |
Total number of polymer chains | 2 |
Total formula weight | 158952.17 |
Authors | Gilbert, N.C.,Rui, Z.,Neau, D.B.,Waight, M.,Bartlett, S.G.,Boeglin, W.E.,Brash, A.R.,Newcomer, M.E. (deposition date: 2011-12-23, release date: 2012-05-02, Last modification date: 2024-02-28) |
Primary citation | Gilbert, N.C.,Rui, Z.,Neau, D.B.,Waight, M.T.,Bartlett, S.G.,Boeglin, W.E.,Brash, A.R.,Newcomer, M.E. Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663. Faseb J., 26:3222-3229, 2012 Cited by PubMed: 22516296DOI: 10.1096/fj.12-205286 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.74 Å) |
Structure validation
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