3V8C

Crystal structure of monoclonal human anti-rhesus D Fc IgG1 t125(yb2/0) double mutant (H310 and H435 in K)

Summary for 3V8C

Entry DOI	10.2210/pdb3v8c/pdb
Related	2J6E 3FJT 3V7M
Descriptor	Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	fc igg1, fc-gamma receptor, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted: P01857
Total number of polymer chains	2
Total formula weight	51383.46
Authors	Menez, R.,Stura, E.A.,Bourel, D.,Siberil, S.,Jorieux, S.,De Romeuf, C.,Ducancel, F.,Fridman, W.H.,Teillaud, J.L. (deposition date: 2011-12-22, release date: 2012-02-22, Last modification date: 2023-09-13)
Primary citation	Siberil, S.,Menez, R.,Jorieux, S.,de Romeuf, C.,Bourel, D.,Fridman, W.H.,Ducancel, F.,Stura, E.A.,Teillaud, J.L. Effect of zinc on human IgG1 and its Fc gamma R interactions. Immunol.Lett., 143:60-69, 2012 Cited by PubMed: 22553781 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation