3V8C
Crystal structure of monoclonal human anti-rhesus D Fc IgG1 t125(yb2/0) double mutant (H310 and H435 in K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Ig gamma-1 chain C region | polymer | 212 | 23957.1 | 2 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (human) | |
| 2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G85856KC) | |||
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A, B | alpha-D-mannopyranose | non-polymer | 180.2 | 5 | Chemie (MAN) | |||
| 6 | A, B | beta-D-galactopyranose | non-polymer | 180.2 | 2 | Chemie (GAL) | |||
| 7 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A, B: 236 - 447 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Lys 310 | His 193 | engineered mutation |
| Lys 435 | His 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47914.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 383.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3085.8 | |
| All* | Total formula weight | 51383.5 |
