3V2X
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Summary for 3V2X
Entry DOI | 10.2210/pdb3v2x/pdb |
Related | 3SO8 3V2O 3V31 |
Descriptor | Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 (3 entities in total) |
Functional Keywords | structural genomics consortium, sgc, ankra2, ank repeat, protein binding, lrp2/megalin |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton : Q9H9E1 Apical cell membrane ; Single- pass type I membrane protein : P98158 |
Total number of polymer chains | 2 |
Total formula weight | 19364.06 |
Authors | Lam, R.,Xu, C.,Bian, C.B.,Kania, J.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-12, release date: 2012-04-04, Last modification date: 2023-09-13) |
Primary citation | Xu, C.,Jin, J.,Bian, C.,Lam, R.,Tian, R.,Weist, R.,You, L.,Nie, J.,Bochkarev, A.,Tempel, W.,Tan, C.S.,Wasney, G.A.,Vedadi, M.,Gish, G.D.,Arrowsmith, C.H.,Pawson, T.,Yang, X.J.,Min, J. Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5:ra39-ra39, 2012 Cited by PubMed: 22649097DOI: 10.1126/scisignal.2002979 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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