3V00

Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.

Summary for 3V00

DescriptorGuanine nucleotide-binding protein G(t) subunit alpha-1/ Guanine nucleotide-binding protein G(i) subunit alpha-1 chimeric protein, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordsgtpase, gtp binding, transducer, signal transduction, cell cycle, signaling protein
Biological sourceBos taurus (bovine,cow,domestic cattle,domestic cow)
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Total number of polymer chains3
Total molecular weight124328.57
Authors
Singh, G.,Cerione, R.A. (deposition date: 2011-12-07, release date: 2012-04-18, Last modification date: 2017-07-26)
Primary citation
Singh, G.,Ramachandran, S.,Cerione, R.A.
A constitutively active G-alpha subunit provide insights into the mechanism of G protein activation
Biochemistry, 51:3232-3240, 2012
PubMed: 22448927 (PDB entries with the same primary citation)
DOI: 10.1021/bi3001984
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.276201.1%9.0%8.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3v00
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Molmil generated image of 3v00
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More Biological unit images

Molmil generated image of 3v00
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Molmil generated image of 3v00
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Molmil generated image of 3v00
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3v00.pdb3.gz [62.77 KB])
Coordinate files for Biological unit (3v00.pdb2.gz [62.22 KB])
Coordinate files for Biological unit (3v00.pdb1.gz [62.93 KB])
Coordinate files for Biological unit (3v00.pdb4.gz [358.73 KB])
Coordinate files for Biological unit (3v00.pdb7.gz [121.06 KB])
Coordinate files for Biological unit (3v00.pdb6.gz [122.58 KB])
Coordinate files for Biological unit (3v00.pdb5.gz [181.25 KB])