3V00
Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, B, A | Guanine nucleotide-binding protein G(t) subunit alpha-1/ Guanine nucleotide-binding protein G(i) subunit alpha-1 chimeric protein | polymer | 356 | 40999.7 | 3 | UniProt (P04695) UniProt (P10824) Pfam (PF00503) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Transducin alpha-1 chain |
2 | C, B, A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
3 | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
C, B, A: 1 - 215 (UniProt: P04695)
C, B, A: 216 - 294 (UniProt: P10824)
C, B, A: 295 - 350 (UniProt: P04695)
PDB | External Database | Details |
---|---|---|
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Pro 56 | Gly 56 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 244 | Lys 248 | engineered mutation |
Asn 247 | Asp 251 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 122999.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1329.6 | |
All* | Total formula weight | 124328.6 |