3UWL
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with 5-formyl tetrahydrofolate
Summary for 3UWL
Entry DOI | 10.2210/pdb3uwl/pdb |
Descriptor | Thymidylate synthase, SULFATE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... (6 entities in total) |
Functional Keywords | methyltransferase, transferase |
Biological source | Enterococcus faecalis More |
Total number of polymer chains | 4 |
Total formula weight | 147715.94 |
Authors | Pozzi, C.,Catalano, A.,Cortesi, D.,Luciani, R.,Ferrari, S.,Fritz, T.,Costi, M.P.,Mangani, S. (deposition date: 2011-12-02, release date: 2012-08-29, Last modification date: 2023-09-13) |
Primary citation | Pozzi, C.,Ferrari, S.,Cortesi, D.,Luciani, R.,Stroud, R.M.,Catalano, A.,Costi, M.P.,Mangani, S. The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism. Acta Crystallogr.,Sect.D, 68:1232-1241, 2012 Cited by PubMed: 22948925DOI: 10.1107/S0907444912026236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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