3UVD
Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in complex with N-Methyl-2-pyrrolidone
Summary for 3UVD
Entry DOI | 10.2210/pdb3uvd/pdb |
Related | 3UV2 3UV4 3UV5 3UVW 3UVX 3UVY 3UW9 |
Descriptor | Transcription activator BRG1, 1-methylpyrrolidin-2-one (3 entities in total) |
Functional Keywords | bromodomain, atp-dependent helicase smarca4, brg1-associated factor 190a, baf190a, mitotic growth and transcription activator, protein brg-1, protein brahma homolog 1, snf2-beta, swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a member 4, structural genomics consortium, sgc, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P51532 |
Total number of polymer chains | 1 |
Total formula weight | 14658.95 |
Authors | Filippakopoulos, P.,Felletar, I.,Picaud, S.,Keates, T.,Muniz, J.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-11-29, release date: 2012-01-18, Last modification date: 2023-09-13) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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