3UV2

Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit BPTF

Summary for 3UV2

Entry DOI	10.2210/pdb3uv2/pdb
Related	3UV4 3UV5 3UVD 3UVW 3UVX 3UVY 3UW9
Descriptor	bromodomain of human nucleosome-remodeling factor subunit BPTF, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL (3 entities in total)
Functional Keywords	bromodomain, bptf, falz, fac1, bromodomain and phd finger-containing transcription factor, fetal alz-50 clone 1 protein, fetal alzheimer antigen, structural genomics consortium, sgc, transcription
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q12830
Total number of polymer chains	1
Total formula weight	15125.20
Authors	Filippakopoulos, P.,Picaud, S.,Keates, T.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-11-29, release date: 2012-01-18, Last modification date: 2023-09-13)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation