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3UP0

Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-delta7-dafachronic acid

Summary for 3UP0
Entry DOI10.2210/pdb3up0/pdb
Related3UP3
DescriptoraceDAF-12, Nuclear receptor coactivator 2, (5beta,14beta,17alpha,25S)-3-oxocholest-7-en-26-oic acid, ... (4 entities in total)
Functional Keywordsnematode, steroid binding protein-transcription complex, steroid binding protein/transcription
Biological sourceAncylostoma ceylanicum
More
Cellular locationNucleus: Q15596
Total number of polymer chains4
Total formula weight59788.58
Authors
Zhi, X.,Zhou, X.E.,Melcher, K.,Motola, D.L.,Gelmedin, V.,Hawdon, J.,Kliewer, S.A.,Mangelsdorf, D.J.,Xu, H.E. (deposition date: 2011-11-17, release date: 2011-12-14, Last modification date: 2024-02-28)
Primary citationZhi, X.,Zhou, X.E.,Melcher, K.,Motola, D.L.,Gelmedin, V.,Hawdon, J.,Kliewer, S.A.,Mangelsdorf, D.J.,Xu, H.E.
Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes.
J.Biol.Chem., 287:4894-4903, 2012
Cited by
PubMed: 22170062
DOI: 10.1074/jbc.M111.315242
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

數據於2024-03-27公開中

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