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3UNW

Crystal Structure of Human GAC in Complex with Glutamate

Summary for 3UNW
Entry DOI10.2210/pdb3unw/pdb
Related3UO9
DescriptorGlutaminase kidney isoform, mitochondrial, GLUTAMIC ACID (3 entities in total)
Functional Keywordsalpha/beta, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cytoplasm, cytosol. Isoform 3: Mitochondrion: O94925
Total number of polymer chains4
Total formula weight236340.48
Authors
DeLaBarre, B.,Gross, S.,Cheng, F.,Gao, Y.,Jha, A.,Jiang, F.,Song, J.J.,Wie, W.,Hurov, J. (deposition date: 2011-11-16, release date: 2011-12-07, Last modification date: 2024-02-28)
Primary citationDeLaBarre, B.,Gross, S.,Fang, C.,Gao, Y.,Jha, A.,Jiang, F.,Song J, J.,Wei, W.,Hurov, J.B.
Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50:10764-10770, 2011
Cited by
PubMed: 22049910
DOI: 10.1021/bi201613d
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.56 Å)
Structure validation

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