3UNW
Crystal Structure of Human GAC in Complex with Glutamate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0006541 | biological_process | glutamine metabolic process |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0006541 | biological_process | glutamine metabolic process |
| C | 0004359 | molecular_function | glutaminase activity |
| C | 0006541 | biological_process | glutamine metabolic process |
| D | 0004359 | molecular_function | glutaminase activity |
| D | 0006541 | biological_process | glutamine metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU A 800 |
| Chain | Residue |
| A | TYR249 |
| A | VAL484 |
| A | GLN285 |
| A | SER286 |
| A | ASN335 |
| A | GLU381 |
| A | ASN388 |
| A | TYR414 |
| A | TYR466 |
| A | GLY483 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GLU B 800 |
| Chain | Residue |
| B | TYR249 |
| B | GLN285 |
| B | SER286 |
| B | ASN335 |
| B | GLU381 |
| B | ASN388 |
| B | TYR414 |
| B | CYS418 |
| B | TYR466 |
| B | GLY483 |
| B | VAL484 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU C 800 |
| Chain | Residue |
| C | TYR249 |
| C | GLN285 |
| C | SER286 |
| C | ASN335 |
| C | GLU381 |
| C | ASN388 |
| C | TYR414 |
| C | TYR466 |
| C | GLY483 |
| C | VAL484 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU D 800 |
| Chain | Residue |
| D | GLN285 |
| D | SER286 |
| D | ASN335 |
| D | GLU381 |
| D | ASN388 |
| D | TYR414 |
| D | CYS418 |
| D | TYR466 |
| D | VAL484 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22049910","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22538822","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24451979","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3CZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VP0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VP1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22049910","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22538822","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24451979","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3CZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VP1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"D3Z7P3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
