3ULU

Structure of quaternary complex of human TLR3ecd with three Fabs (Form1)

Summary for 3ULU

• Entry DOI: 10.2210/pdb3ulu/pdb
• Related: 3ULS 3ULV
• Descriptor: Toll-like receptor 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: toll-like receptor-3, tlr3, innate immunity, leucine rich repeat, lrr, immunoglobulin, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 225961.43

Authors

Luo, J.,Gilliland, G.L.,Obmolova, O.,Malia, T.,Teplyakov, A. (deposition date: 2011-11-11, release date: 2012-05-23, Last modification date: 2023-09-13)

• Primary citation: Luo, J.,Obmolova, G.,Malia, T.J.,Wu, S.J.,Duffy, K.E.,Marion, J.D.,Bell, J.K.,Ge, P.,Zhou, Z.H.,Teplyakov, A.,Zhao, Y.,Lamb, R.J.,Jordan, J.L.,San Mateo, L.R.,Sweet, R.W.,Gilliland, G.L.; Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.; J.Mol.Biol., 421:112-124, 2012; PubMed: 22579623; DOI: 10.1016/j.jmb.2012.05.006

Experimental method

X-RAY DIFFRACTION (3.52 Å)