3UH2

Tankyrase-1 in complexed with PJ34

Summary for 3UH2

• Entry DOI: 10.2210/pdb3uh2/pdb
• Related: 3UH4
• Descriptor: Tankyrase-1, ZINC ION, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, ... (5 entities in total)
• Functional Keywords: transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O95271
• Total number of polymer chains: 2
• Total formula weight: 52611.90

Authors

Kirby, C.A.,Stams, T. (deposition date: 2011-11-03, release date: 2012-02-15, Last modification date: 2023-09-13)

• Primary citation: Kirby, C.A.,Cheung, A.,Fazal, A.,Shultz, M.D.,Stams, T.; Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939.; Acta Crystallogr.,Sect.F, 68:115-118, 2012; PubMed: 22297980; DOI: 10.1107/S1744309111051219

Experimental method

X-RAY DIFFRACTION (2 Å)