3UF5

Crystal structure of the mouse Colony-Stimulating Factor 1 (mCSF-1) cytokine

Summary for 3UF5

Entry DOI	10.2210/pdb3uf5/pdb
Related	3EJJ 3UEZ 3UF2
Descriptor	Macrophage colony-stimulating factor 1, CALCIUM ION (3 entities in total)
Functional Keywords	hematopoietic cytokine, rtkiii, four-helix bundle, cytokine
Biological source	Mus musculus (mouse)
Cellular location	Cell membrane; Single-pass membrane protein (By similarity). Processed macrophage colony-stimulating factor 1: Secreted, extracellular space (By similarity): P07141
Total number of polymer chains	2
Total formula weight	35904.53
Authors	Elegheert, J.,Bracke, N.,Bekaert, A.,Savvides, S.N. (deposition date: 2011-10-31, release date: 2012-08-22, Last modification date: 2013-07-17)
Primary citation	Elegheert, J.,Bracke, N.,Pouliot, P.,Gutsche, I.,Shkumatov, A.V.,Tarbouriech, N.,Verstraete, K.,Bekaert, A.,Burmeister, W.P.,Svergun, D.I.,Lambrecht, B.N.,Vergauwen, B.,Savvides, S.N. Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 Nat.Struct.Mol.Biol., 19:938-947, 2012 Cited by PubMed: 22902366 DOI: 10.1038/nsmb.2367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation