3U7Y
Structure of NIH45-46 Fab in complex with gp120 of 93TH057 HIV
Summary for 3U7Y
Entry DOI | 10.2210/pdb3u7y/pdb |
Related | 3U7W |
Descriptor | NIH45-46 heavy chain, Ig gamma-1 chain C region, Envelope glycoprotein gp160, NIH45-46 light chain, Ig kappa chain C region, ... (8 entities in total) |
Functional Keywords | ig fold, gp120, anti hiv, glycosylation, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 90594.78 |
Authors | Diskin, R.,Bjorkman, P.J. (deposition date: 2011-10-14, release date: 2011-11-16, Last modification date: 2023-09-13) |
Primary citation | Diskin, R.,Scheid, J.F.,Marcovecchio, P.M.,West, A.P.,Klein, F.,Gao, H.,Gnanapragasam, P.N.,Abadir, A.,Seaman, M.S.,Nussenzweig, M.C.,Bjorkman, P.J. Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design. Science, 334:1289-1293, 2011 Cited by PubMed: 22033520DOI: 10.1126/science.1213782 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4478 Å) |
Structure validation
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