3U6F
Mouse TREX1 D200N mutant
Summary for 3U6F
Entry DOI | 10.2210/pdb3u6f/pdb |
Descriptor | Three prime repair exonuclease 1, 5'-D(*GP*AP*CP*G)-3', 1,4-BUTANEDIOL, ... (5 entities in total) |
Functional Keywords | rnase h fold, 3' exonuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Mus musculus (mouse) |
Cellular location | Nucleus (By similarity): Q91XB0 |
Total number of polymer chains | 4 |
Total formula weight | 70079.35 |
Authors | Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T. (deposition date: 2011-10-12, release date: 2011-12-28, Last modification date: 2024-02-28) |
Primary citation | Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T. Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease. Dna Repair, 11:65-73, 2012 Cited by PubMed: 22071149DOI: 10.1016/j.dnarep.2011.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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