3U40

Crystal structure of a purine nucleoside phosphorylase from Entamoeba histolytica bound to adenosine

Summary for 3U40

Entry DOI	10.2210/pdb3u40/pdb
Related	3TL6
Descriptor	Purine nucleoside phosphorylase, ADENOSINE, NITRATE ION, ... (5 entities in total)
Functional Keywords	structural genomics, seattle structural genomics center for infectious disease, ssgcid, purine salvage, maltose binding protein, expression rescue, co-crystal, transferase
Biological source	Entamoeba histolytica
Total number of polymer chains	6
Total formula weight	161717.70
Authors	Edwards, T.E.,Gardberg, A.S.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2011-10-06, release date: 2011-10-19, Last modification date: 2023-09-13)
Primary citation	Hewitt, S.N.,Choi, R.,Kelley, A.,Crowther, G.J.,Napuli, A.J.,Van Voorhis, W.C. Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallogr.,Sect.F, 67:1006-1009, 2011 Cited by PubMed: 21904041 DOI: 10.1107/S1744309111022159 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation