3TYE
Dihydropteroate Synthase in complex with DHP-STZ
Summary for 3TYE
| Entry DOI | 10.2210/pdb3tye/pdb |
| Related | 1TWS |
| Descriptor | Dihydropteroate synthase, 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | anthracis, folate biosynthesis, dihydropteroate, pterine, tim barrel, transferase |
| Biological source | Bacillus anthracis (anthrax,anthrax bacterium) |
| Total number of polymer chains | 2 |
| Total formula weight | 67496.99 |
| Authors | Yun, M.-K.,White, S.W. (deposition date: 2011-09-24, release date: 2012-03-14, Last modification date: 2023-09-13) |
| Primary citation | Yun, M.K.,Wu, Y.,Li, Z.,Zhao, Y.,Waddell, M.B.,Ferreira, A.M.,Lee, R.E.,Bashford, D.,White, S.W. Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335:1110-1114, 2012 Cited by PubMed: 22383850DOI: 10.1126/science.1214641 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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