3TYE

Dihydropteroate Synthase in complex with DHP-STZ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydropteroate synthase	polymer	297	32883.7	2	UniProt (Q81VW8) Pfam (PF00809)	Bacillus anthracis (anthrax anthrax bacterium)
2	C (A)	4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide	non-polymer		432.5	1	Chemie (XTZ)
3	D, E, F, G, J... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4	H (B)	2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one	non-polymer		177.2	1	Chemie (XHP)
5	I (B)	4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide	non-polymer		255.3	1	Chemie (YTZ)
6	O, P (A, B)	water	water		18.0	84	Chemie (HOH)

Sequence modifications

A, B: -6 - 277 (UniProt: Q81VW8)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65767.5
Non-Polymers*	Number of molecules	12
	Total formula weight	1729.5
All*	Total formula weight	67497.0

*Water molecules are not included.