3TWQ
Crystal structure of ARC4 from human Tankyrase 2 (apo form)
Summary for 3TWQ
| Entry DOI | 10.2210/pdb3twq/pdb |
| Related | 3TWR 3TWS 3TWT 3TWU 3TWV 3TWW 3TWX |
| Descriptor | Tankyrase-2, SULFATE ION, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | ankyrin repeat, protein-protein interaction, poly(adp-ribosyl)ation, substrate recruitment, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q9H2K2 |
| Total number of polymer chains | 2 |
| Total formula weight | 38365.29 |
| Authors | Guettler, S.,Sicheri, F. (deposition date: 2011-09-22, release date: 2011-12-07, Last modification date: 2024-02-28) |
| Primary citation | Guettler, S.,Larose, J.,Petsalaki, E.,Gish, G.,Scotter, A.,Pawson, T.,Rottapel, R.,Sicheri, F. Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147:1340-1354, 2011 Cited by PubMed: 22153077DOI: 10.1016/j.cell.2011.10.046 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.151 Å) |
Structure validation
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