3TUG

Crystal structure of the HECT domain of ITCH E3 ubiquitin ligase

Summary for 3TUG

• Entry DOI: 10.2210/pdb3tug/pdb
• Descriptor: E3 ubiquitin-protein ligase Itchy homolog, CHLORIDE ION, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, catalytic domain, e3 ligase, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane: Q96J02
• Total number of polymer chains: 1
• Total formula weight: 47525.59

Authors

Dong, A.,Dobrovetsky, E.,Xue, S.,Butler, C.,Wernimont, A.,Walker, J.R.,Tempel, W.,Dhe-Paganon, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Tong, Y.,Structural Genomics Consortium (SGC) (deposition date: 2011-09-16, release date: 2011-10-12, Last modification date: 2023-09-13)

• Primary citation: Dobrovetsky, E.,Dong, A.,Xue, S.,Butler, C.,Wernimont, A.,Walker, J.R.,Tempel, W.,Dhe-Paganon, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Tong, Y.; Crystal structure of the HECT domain of ITCH E3 ubiquitin ligase; To be Published,

Experimental method

X-RAY DIFFRACTION (2.27 Å)