3TQ8
Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with trimethoprim
Summary for 3TQ8
Entry DOI | 10.2210/pdb3tq8/pdb |
Related | 3TQ9 3TQA 3TQB |
Descriptor | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM, ... (4 entities in total) |
Functional Keywords | dihydrofolate reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Coxiella burnetii |
Total number of polymer chains | 1 |
Total formula weight | 21959.90 |
Authors | Franklin, M.C.,Cassidy, M.,Hillerich, B.,Love, J. (deposition date: 2011-09-09, release date: 2011-11-02, Last modification date: 2024-04-03) |
Primary citation | Franklin, M.C.,Cheung, J.,Rudolph, M.J.,Burshteyn, F.,Cassidy, M.,Gary, E.,Hillerich, B.,Yao, Z.K.,Carlier, P.R.,Totrov, M.,Love, J.D. Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83:2124-2136, 2015 Cited by PubMed: 26033498DOI: 10.1002/prot.24841 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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