3TPY

Crystal structure of M-PMV dUTPase with a mixed population of substrate (dUPNPP) and post-inversion product (dUMP) in the active sites

Summary for 3TPY

• Entry DOI: 10.2210/pdb3tpy/pdb
• Related: 2D4L 2D4M 2D4N 3TP1 3TPN 3TPS 3TPW 3TQ3 3TQ4 3TQ5 3TRL 3TRN 3TS6 3TSL 3TTA
• Descriptor: DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE, MAGNESIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• Functional Keywords: jelly roll, hydrolase
• Biological source: Mason-Pfizer monkey virus (MPMV)
• Total number of polymer chains: 1
• Total formula weight: 17077.16

Authors

Barabas, O.,Nemeth, V.,Vertessy, B.G. (deposition date: 2011-09-08, release date: 2011-10-12, Last modification date: 2023-09-13)

• Primary citation: Barabas, O.,Nemeth, V.,Bodor, A.,Perczel, A.,Rosta, E.,Kele, Z.,Zagyva, I.,Szabadka, Z.,Grolmusz, V.I.,Wilmanns, M.,Vertessy, B.G.; Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion; to be published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)