3TPK
Crystal structure of the oligomer-specific KW1 antibody fragment
Summary for 3TPK
Entry DOI | 10.2210/pdb3tpk/pdb |
Descriptor | Immunoglobulin heavy chain antibody variable domain KW1, BENZAMIDINE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | immunoglobulin heavy chain domains, vhh, complementarity determining regions, cdr, oligomer-specific, alzheimer's disease, amyloid, immune system |
Biological source | Camelidae |
Total number of polymer chains | 1 |
Total formula weight | 15284.82 |
Authors | Parthier, C.,Morgado, I.,Stubbs, M.T.,Fandrich, M. (deposition date: 2011-09-08, release date: 2012-07-11, Last modification date: 2023-09-13) |
Primary citation | Morgado, I.,Wieligmann, K.,Bereza, M.,Ronicke, R.,Meinhardt, K.,Annamalai, K.,Baumann, M.,Wacker, J.,Hortschansky, P.,Malesevic, M.,Parthier, C.,Mawrin, C.,Schiene-Fischer, C.,Reymann, K.G.,Stubbs, M.T.,Balbach, J.,Gorlach, M.,Horn, U.,Fandrich, M. Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment. Proc.Natl.Acad.Sci.USA, 109:12503-12508, 2012 Cited by PubMed: 22814377DOI: 10.1073/pnas.1206433109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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