3TOP
Crystral Structure of the C-terminal Subunit of Human Maltase-Glucoamylase in Complex with Acarbose
Summary for 3TOP
Entry DOI | 10.2210/pdb3top/pdb |
Related | 3TON |
Related PRD ID | PRD_900007 |
Descriptor | Maltase-glucoamylase, intestinal, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | membrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Apical cell membrane; Single-pass type II membrane protein: O43451 |
Total number of polymer chains | 2 |
Total formula weight | 208745.59 |
Authors | |
Primary citation | Ren, L.M.,Qin, X.H.,Cao, X.F.,Wang, L.L.,Bai, F.,Bai, G.,Shen, Y. Structural insight into substrate specificity of human intestinal maltase-glucoamylase Protein Cell, 2:827-836, 2011 Cited by PubMed: 22058037DOI: 10.1007/s13238-011-1105-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.881 Å) |
Structure validation
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