3TNP

Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme

Summary for 3TNP

• Entry DOI: 10.2210/pdb3tnp/pdb
• Related: 3TNQ 3TNR
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit (3 entities in total)
• Functional Keywords: pka riib tetrameric holoenzyme, transferase
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm: P05132; Cytoplasm (By similarity): P31324
• Total number of polymer chains: 4
• Total formula weight: 174022.48

Authors

Zhang, P.,Smith-Nguyen, E.V.,Keshwani, M.M.,Deal, M.S.,Kornev, A.P.,Taylor, S.S. (deposition date: 2011-09-01, release date: 2012-02-01, Last modification date: 2013-02-27)

• Primary citation: Zhang, P.,Smith-Nguyen, E.V.,Keshwani, M.M.,Deal, M.S.,Kornev, A.P.,Taylor, S.S.; Structure and allostery of the PKA RIIbeta tetrameric holoenzyme; Science, 335:712-716, 2012; PubMed: 22323819; DOI: 10.1126/science.1213979

Experimental method

X-RAY DIFFRACTION (2.3 Å)