3TNP
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (C, F) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40817.3 | 2 | UniProt (P05132) Pfam (PF00069) | Mus musculus (mouse) | PKA C-alpha |
| 2 | B, D (B, E) | cAMP-dependent protein kinase type II-beta regulatory subunit | polymer | 416 | 46194.0 | 2 | UniProt (P31324) Pfam (PF02197) Pfam (PF00027) | Mus musculus (mouse) | |
| 3 | E, F, G, H (C, B, F, E) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 416 (UniProt: P31324)
| PDB | External Database | Details |
|---|---|---|
| Lys 230 | Arg 230 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174022.5 | |
| All* | Total formula weight | 174022.5 |
