3TDV

Structure of the GDP complex of wild-type aminoglycoside 2'-phosphotransferase-IIIa

Summary for 3TDV

• Entry DOI: 10.2210/pdb3tdv/pdb
• Related: 3TDW
• Descriptor: Gentamicin resistance protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kinase, phosphoryl transfer, antibiotic resistance, gentamicin, transferase
• Biological source: Enterococcus gallinarum
• Total number of polymer chains: 2
• Total formula weight: 70488.69

Authors

Smith, C.A.,Vakulenko, S.B. (deposition date: 2011-08-11, release date: 2012-03-07, Last modification date: 2024-02-28)

• Primary citation: Smith, C.A.,Toth, M.,Frase, H.,Byrnes, L.J.,Vakulenko, S.B.; Aminoglycoside-2' phosphotransferase-IIIa (APH(2')-IIIa) prefers GTP over ATP: Structural templates for nucleotide recognition in the bacterial aminoglycoside-2' kinases.; J.Biol.Chem., 287:12893-12903, 2012; PubMed: 22367198; DOI: 10.1074/jbc.M112.341206

Experimental method

X-RAY DIFFRACTION (2.2 Å)