3TCZ
Human Pin1 bound to cis peptidomimetic inhibitor
Summary for 3TCZ
Entry DOI | 10.2210/pdb3tcz/pdb |
Related | 1F8A 1PIN 2ITK 2Q5A 3TDB |
Descriptor | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N~2~-({(1R,2Z)-2-[(2R)-2-(formylamino)-3-(phosphonooxy)propylidene]cyclopentyl}carbonyl)-L-argininamide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (4 entities in total) |
Functional Keywords | ppiase domain, ww domain, peptidyl-prolyl isomerase, isomerase-inhibitor complex, isomerase/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q13526 |
Total number of polymer chains | 1 |
Total formula weight | 18412.45 |
Authors | |
Primary citation | Zhang, M.,Wang, X.J.,Chen, X.,Bowman, M.E.,Luo, Y.,Noel, J.P.,Ellington, A.D.,Etzkorn, F.A.,Zhang, Y. Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code. Acs Chem.Biol., 7:1462-1470, 2012 Cited by PubMed: 22670809DOI: 10.1021/cb3000887 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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