3TCZ
Human Pin1 bound to cis peptidomimetic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | polymer | 158 | 17609.6 | 1 | UniProt (Q13526) Pfam (PF00397) Pfam (PF00639) In PDB | Homo sapiens (human) | Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1 |
| 2 | A | N~2~-({(1R,2Z)-2-[(2R)-2-(formylamino)-3-(phosphonooxy)propylidene]cyclopentyl}carbonyl)-L-argininamide | non-polymer | 448.4 | 1 | Chemie (R2Z) | |||
| 3 | A | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 4 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 6 - 163 (UniProt: Q13526)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Arg 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17609.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 802.8 | |
| All* | Total formula weight | 18412.5 |
