3TBW

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (A2G, V3P, Y4S)

Summary for 3TBW

• Entry DOI: 10.2210/pdb3tbw/pdb
• Related: 1S7U 1S7V 1S7W 1S7X 3QUK 3QUL 3TBS 3TBT 3TBV 3TBX 3TBY
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, GLYCOPROTEIN GPC, ... (4 entities in total)
• Functional Keywords: murine mhc, lcmv, receptor binding, beta2-microglobulin, immune system, t cell recognition, antigen presentation, altered peptide ligand, agonism, antagonism, t cell receptor, cd8, cell surface, immune system-agonist complex, immune system/agonist
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G1: Virion membrane ; Peripheral membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P07399
• Total number of polymer chains: 12
• Total formula weight: 178980.62

Authors

Duru, A.D.,Allerbring, E.B.,Uchtenhagen, H.,Mazumdar, P.A.,Badia-Martinez, D.,Madhurantakam, C.,Sandalova, T.,Nygren, P.,Achour, A. (deposition date: 2011-08-08, release date: 2012-08-08, Last modification date: 2024-11-20)

• Primary citation: Duru, A.D.,Allerbring, E.B.,Uchtenhagen, H.,Mazumdar, P.A.,Badia-Martinez, D.,Madhurantakam, C.,Sandalova, T.,Nygren, P.,Achour, A.; Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition; To be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)