Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3T60

5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase

Summary for 3T60
Entry DOI10.2210/pdb3t60/pdb
Related3T64
DescriptorDeoxyuridine 5'-triphosphate nucleotidohydrolase, putative, 2',5'-dideoxy-5'-(tritylamino)uridine, GLYCEROL, ... (4 entities in total)
Functional Keywordstrimeric dutpase, dutp binding, nucleus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourcePlasmodium falciparum
Total number of polymer chains3
Total formula weight63707.86
Authors
Primary citationHampton, S.E.,Baragana, B.,Schipani, A.,Bosch-Navarrete, C.,Musso-Buendia, J.A.,Recio, E.,Kaiser, M.,Whittingham, J.L.,Roberts, S.M.,Shevtsov, M.,Brannigan, J.A.,Kahnberg, P.,Brun, R.,Wilson, K.S.,Gonzalez-Pacanowska, D.,Johansson, N.G.,Gilbert, I.H.
Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
Chemmedchem, 6:1816-1831, 2011
Cited by
PubMed: 22049550
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.396 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon