3T60

5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative	polymer	181	20674.3	3	UniProt (Q8II92) Pfam (PF00692) In PDB	Plasmodium falciparum
2	A, B, C	2',5'-dideoxy-5'-(tritylamino)uridine	non-polymer		469.5	3	Chemie (DUA)
3	A, B, C	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 173 (UniProt: Q8II92)

PDB	External Database	Details
Leu 174	-	expression tag
Glu 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	62023.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1684.9
All*	Total formula weight	63707.9

*Water molecules are not included.