3T1I
Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations
Summary for 3T1I
Entry DOI | 10.2210/pdb3t1i/pdb |
Descriptor | Double-strand break repair protein MRE11A, MANGANESE (II) ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (5 entities in total) |
Functional Keywords | dna repair, mrn complex, metallophosphatase, exonuclease, endonuclease, rad50, nbs1, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): P49959 |
Total number of polymer chains | 4 |
Total formula weight | 201428.71 |
Authors | |
Primary citation | Park, Y.B.,Chae, J.,Kim, Y.,Cho, Y. Crystal structure of human mre11: understanding tumorigenic mutations Structure, 19:1591-1602, 2011 Cited by PubMed: 22078559DOI: 10.1016/j.str.2011.09.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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