3T1H
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
Summary for 3T1H
Entry DOI | 10.2210/pdb3t1h/pdb |
Related | 1J5E 2L9E 2UUC 3T1Y |
Descriptor | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (26 entities in total) |
Functional Keywords | protein synthesis, trna, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 23 |
Total formula weight | 790487.05 |
Authors | Murphy, F.V.,Vendeix, F.A.P.,Cantara, W.,Leszczynska, G.,Gustilo, E.M.,Sproat, B.,Malkiewicz, A.A.P.,Agris, P.F. (deposition date: 2011-07-21, release date: 2012-01-25, Last modification date: 2023-09-13) |
Primary citation | Vendeix, F.A.,Murphy, F.V.,Cantara, W.A.,Leszczynska, G.,Gustilo, E.M.,Sproat, B.,Malkiewicz, A.,Agris, P.F. Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416:467-485, 2012 Cited by PubMed: 22227389DOI: 10.1016/j.jmb.2011.12.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.11 Å) |
Structure validation
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