3T11
Dimeric inhibitor of HIV-1 protease.
Summary for 3T11
Entry DOI | 10.2210/pdb3t11/pdb |
Descriptor | HIV-1 Protease, (3S,11S)-11-(3-chloro-4-hydroxy-5-methoxyphenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | hiv-1 protease, beta barel, retroviral aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) |
Cellular location | Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367 |
Total number of polymer chains | 2 |
Total formula weight | 22693.08 |
Authors | Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J. (deposition date: 2011-07-21, release date: 2012-08-22, Last modification date: 2023-09-13) |
Primary citation | Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J. Dimeric inhibitor of HIV-1 protease. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
Download full validation report