3T11
Dimeric inhibitor of HIV-1 protease.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 Protease | polymer | 99 | 10803.8 | 2 | UniProt (P03367) Pfam (PF00077) | Human immunodeficiency virus type 1 (HIV-1) | PR, Retropepsin |
| 2 | C, F (A, B) | (3S,11S)-11-(3-chloro-4-hydroxy-5-methoxyphenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one | non-polymer | 446.9 | 2 | Chemie (3T1) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E, G (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21607.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1085.6 | |
| All* | Total formula weight | 22693.1 |
