3SZG

Crystal structure of C176A glutamine-dependent NAD+ synthetase from M. tuberculosis bound to AMP/PPi and NaAD+

Summary for 3SZG

Entry DOI	10.2210/pdb3szg/pdb
Related	3DLA 3SDB 3SEQ 3SEZ 3SYT
Descriptor	Glutamine-dependent NAD(+) synthetase, NICOTINIC ACID ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ... (6 entities in total)
Functional Keywords	glutamine-amidotransferase, glutaminase, glutamine-dependent nad+ synthetase, ligase, ammonia tunneling, atp binding, nad, nucleotide binding
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	4
Total formula weight	304324.08
Authors	Chuenchor, W.,Doukov, T.,Gerratana, B. (deposition date: 2011-07-19, release date: 2012-04-11, Last modification date: 2023-09-13)
Primary citation	Chuenchor, W.,Doukov, T.I.,Resto, M.,Chang, A.,Gerratana, B. Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase. Biochem.J., 443:417-426, 2012 Cited by PubMed: 22280445 DOI: 10.1042/BJ20112210 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation