3SRZ

Clostridium difficile toxin A (TcdA) glucolsyltransferase domain bound to UDP-glucose

Summary for 3SRZ

• Entry DOI: 10.2210/pdb3srz/pdb
• Related: 3SS1
• Descriptor: Toxin A, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (4 entities in total)
• Functional Keywords: glucosyltransferase, transferase
• Biological source: Clostridium difficile
• Total number of polymer chains: 1
• Total formula weight: 65020.91

Authors

Pruitt, R.N.,Chumbler, N.M.,Farrow, M.A.,Seeback, S.A.,Friedman, D.B.,Spiller, B.W.,Lacy, D.B. (deposition date: 2011-07-07, release date: 2012-02-01, Last modification date: 2024-02-28)

• Primary citation: Pruitt, R.N.,Chumbler, N.M.,Rutherford, S.A.,Farrow, M.A.,Friedman, D.B.,Spiller, B.,Lacy, D.B.; Structural Determinants of Clostridium difficile Toxin A Glucosyltransferase Activity.; J.Biol.Chem., 287:8013-8020, 2012; PubMed: 22267739; DOI: 10.1074/jbc.M111.298414

Experimental method

X-RAY DIFFRACTION (2.58 Å)