3SRZ
Clostridium difficile toxin A (TcdA) glucolsyltransferase domain bound to UDP-glucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 1542 |
| Chain | Residue |
| A | ASP287 |
| A | GLU514 |
| A | UPG556 |
| A | HOH589 |
| A | HOH614 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE UPG A 556 |
| Chain | Residue |
| A | LEU264 |
| A | ALA265 |
| A | SER268 |
| A | ASP269 |
| A | ARG272 |
| A | TYR283 |
| A | ASP285 |
| A | VAL286 |
| A | ASP287 |
| A | ASN383 |
| A | GLN384 |
| A | THR464 |
| A | GLY469 |
| A | GLU514 |
| A | SER517 |
| A | LEU518 |
| A | TRP519 |
| A | HOH578 |
| A | HOH589 |
| A | HOH606 |
| A | HOH614 |
| A | MN1542 |
| A | VAL100 |
| A | TRP101 |
| A | ILE102 |
| A | ASN138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:22747490, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:4DMV, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
| Chain | Residue | Details |
| A | VAL100 | |
| A | SER268 | |
| A | SER517 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
| Chain | Residue | Details |
| A | ASN138 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0007744|PDB:3SS1 |
| Chain | Residue | Details |
| A | ASP285 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:22747490, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:3SS1, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
| Chain | Residue | Details |
| A | ASP287 | |
| A | GLU514 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000305|PubMed:19553670 |
| Chain | Residue | Details |
| A | LEU542 |
