3SOA
Full-length human CaMKII
Summary for 3SOA
Entry DOI | 10.2210/pdb3soa/pdb |
Descriptor | Calcium/calmodulin-dependent protein kinase type II subunit alpha with a beta 7 linker, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile (2 entities in total) |
Functional Keywords | kinase, protein kinase, phosphorylation, calcium/calmodulin, cytosolic, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cell junction, synapse, presynaptic cell membrane (By similarity): Q9UQM7 |
Total number of polymer chains | 1 |
Total formula weight | 51176.45 |
Authors | Chao, L.H.,Kuriyan, J. (deposition date: 2011-06-30, release date: 2011-08-31, Last modification date: 2023-09-13) |
Primary citation | Chao, L.H.,Stratton, M.M.,Lee, I.H.,Rosenberg, O.S.,Levitz, J.,Mandell, D.J.,Kortemme, T.,Groves, J.T.,Schulman, H.,Kuriyan, J. A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca(2+)/Calmodulin- Dependent Kinase II Holoenzyme. Cell(Cambridge,Mass.), 146:732-745, 2011 Cited by PubMed: 21884935DOI: 10.1016/j.cell.2011.07.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5501 Å) |
Structure validation
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